

"Review of the Vioxx documents revealed 3 key themes that were related to the design and marketing objectives of the ADVANTAGE trial:
-The trial emerged from the marketing division with a marketing objective;
-Merck's marketing division collected, analyzed, and disseminated both the scientific and the marketing data;
-and Merck did not reveal the marketing purposes of the trial to participants, physician-investigators, and institutional review board members."
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