The world's priciest medicine, Soliris, costs an astonishing $409,500 a year for the average patient, Forbes.com said yesterday in its survey of the most expensive medicines on earth.
Most of the pricey pharmaceuticals target rare disorders that affect relatively few people.
Soliris, made by Alexion Pharmaceuticals, is given intravenously to treat paroxysmal nocturnal hemoglobinuria, or PNH, a rare disorder in which the immune system destroys red blood cells. About 8,000 Americans suffer from the disease, Forbes said.
The Top Nine, according to Forbes:
- Soliris (eculizumab), for PNH, annual cost: $409,500. Manufacturer: Alexion Pharmaceuticals
- Elaprase (idursulfase), for Hunter syndrome, annual cost: $375,000. Manufacturer: Shire Pharmaceuticals
- Naglazyme (galsulfase), for Maroteaux-Lamy syndrome (mucopolysccharidosis IV), annual cost: $365,000. Manufacturer: BioMarin Pharmaceutical
- Cinryze (C1 esterase inhibitor), for hereditary angiodema, annual cost: $350,000. Manufacturer: ViroPharma
- Myozyme (alglucosidase alpha), for Pompe disease, annual cost: $300,000. Manufacturer: Genyzme
- Arcalyst (rilonacept), for cryopyrin-associated periodic syndromes, annual cost: $250,000. Manufacturer: Regeneron
- Fabrazyme (agalsidase beta), for Fabry disease, annual cost: $200,000. Manufacturer: Genzyme
- Cerezyme (imiglucerase), for Gaucher disease, annual cost: $200,000. Manufacturer: Genzyme
- Aldurazyme (laronidase), for Hurler syndrome (mucopolysaccharidosis I), annual cost: $200,000. Manufacturer: Genzyme, BioMarin Pharmaceutical.
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