Francis specified that Novartis will likely launch biosimilar versions of AbbVie's Humira (adalimumab), Amgen's Enbrel (etanercept) and Neulasta (pegfilgrastim), Johnson & Johnson's Remicade (infliximab) and Roche's Rituxan (rituximab) within the next four years. The five drugs amassed combined sales of approximately $44 billion in 2015, according to Novartis.
The company indicated that it would pursue an "aggressive" strategy that involves the submission of 11 regulatory filings between 2015 and 2017, noting that Sandoz has already announced six of these in the last 12 months. Most recently, the European Medicines Agency accepted the drugmaker's submission for its Rituxan biosimilar in May. Meanwhile, Novartis said Sandoz's early-stage pipeline includes assets in oncology and other specialty therapeutic areas, "with plans to start new programmes every year." The company also suggested that investments of more than $1 billion, from 2010 through to 2020, in two bio-manufacturing facilities in Austria "position Sandoz to deliver biosimilars at an unprecedented scale."
Novartis launched its Omnitrope (somatropin) biosimilar referencing Pfizer's recombinant human growth hormone Genotropin (somatropin) in Europe in 2006, marking the first availability of a biosimilar therapy anywhere globally.