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miércoles, 20 de septiembre de 2023

USA: Stop a Ozempic...


 

It seemed like only a matter of time before someone would close this valve. After months of off-label prescribing of Ozempic, propelled by celebrity hype of the diabetes drug which has gained popularity as a weight-loss treatment, some payers have decided to rein in the practice.

According to a report in The Washington Post last week, some 14 Anthem Blue Cross Blue Shield plans cautioned healthcare providers in several states about prescribing Ozempic to non-diabetic patients. As the “education” letter noted, an inquiry undertaken of those physicians’ claims by the plan’s “Special Investigations Unit” revealed that 60% of patients prescribed Ozempic lacked “sufficient evidence” of diabetes, the product’s Food and Drug Administration-approved use.


Such prescribing could put patients at risk, the insurer warned, threatening the 150 or so prescribers who received the letter that it would refer “suspected inappropriate or fraudulent activity…to the state licensure board, federal and/or state law enforcement.” What’s more, the trend has led to nationwide shortages of the drug for diabetics.

Those warnings portend a future reckoning with regard to new drugs like Ozempic, driven by celebrity and social-media buzz around the medications, which are disrupting the way obesity is treated. The new crop of products, known as GLPs, has proven to be highly safe and effective and is stoking a mad dash by patients to access them and by pharma companies to satisfy the market.

But their high costs – the drugs list for $900 or more per month – put payers in a pickle: should they give the GLPs a warm reception, potentially saving money on downstream medical expenses, or tamp down on what’s shaping up to be a colossal short-term liability?

While carriers are frowning on off-label prescribing now, the spigot could reopen if studies pan out showing that Ozempic and its cousins have cardiovascular and other wider health benefits. Novo Nordisk and Eli Lilly are studying whether use of these drugs decreases comorbidities. 

Más

martes, 10 de enero de 2017

NOVARTIS: New Year's Day en Grecia de suicidio, corrupción y whistleblowers...

«It’s a combination for us of hiring the right people, 
training them when they get here, 
and thirdly, you need the ability to identify it 
and wipe it out as soon as you see it»*
Joe Jimenez Novartis CEO


New Year’s day around 5 pm in the afternoon. A man is sitting at the Galaxy Bat at the 13th floor of Hilton hotel in Athens. 
Greek media report that the man had suddenly started to threaten that he would jump. The hotel personnel called the police. The suicide was averted due to a police negotiator who managed to persuade the desperate man to abandon his plans and put an end to his life. 

After an hour of negotiations, the man broke down and with tears in his eyes he told the policemen that he would not allow to bear the burden for all the mistakes of his employer. He said that he was fearing for his life. 

According to media, the 44-year-old is a former high-ranking manager of multinational pharma giant Novartis, target of investigation by the FBI and the US-Justice. 

The Greek manager had been recently relocated from Greece to the company’s headquarters in Basel, Switzerland. 

Three weeks ago, Greek Justice Minister Stavros Kontonis sent to Supreme Court prosecutor media reports according to which a big pharma company bribed doctors and public officials in order to boost prescriptions and the companies sales. The prosecutor should investigate media reports that two executives of Novartis in Greece had told US authorities that “the company used unfair methods to improve the company’s position in the Greek market for many years.” 


(*)The company (Novartis) has 35,000 sales and marketing representatives around the world. 
PS I remember to see several of them standing line in the corridors of IKA when I’d go there for my mom’s prescription medicine. 
The rate was usual 1-2 patients: 4-5 Novartis’ representatives – for a popular drug for a specific illness- awaiting outside the doctor’s door. The rude representatives, young men and women in black and white suits, would normally push aside the patients who had an appointment and enter the office claiming they had other clients waiting.(Ver)

Ver:

NOVARTIS: Ahora la multa es de $ USA 390 millones (por sobornar...)

USA: Novartis acusada de sobornar para prescribir...

CHINA: "Zorro" ataca Alcon...de Novartis.


The case was revealed by news website iefimerida.gr on December 12th 2016.
According to the website, the two executives had given the relevant testimony to the US Securities and Exchange Commission investigating the pharma company last August. 



According to NewsIt.gr, the name of the man was included in the list the whistle-blowers have given to US authorities. (Ver)


Ver:
Whistle-blowers/ BIG PHARMA: "El enemigo esta adentro..."



Greek authorities have also requested the assistance of U.S. authorities which, along with the Securities and Exchange Commission (SEC) first launched an investigation into the drug maker two years ago. According to the reports, two executives of Novartis in Greece had submitted to U.S. authorities hundreds of documents which prove payments to private doctors and doctors who work in the public healthcare system (more than 4,000 in total), in an effort to promote the company’s products. 

The prosecution requested that U.S. authorities share any data pertaining to the Greek part of the scandal. 

State broadcaster ERT TV reported on Wednesday morning that agents from the US Federal Bureau of Investigation have arrived in Athens in order to investigate Novartis together with Greek authorities. 
More than 178 people have been questioned on alleged illegal discounts offered by Novartis from 2006 to 2014 to some 4,000 public and private doctors in order to prescribe certain drugs and boost company sales. (Más)

 Greek prosecutors raid Novartis offices, disclose wide-ranging probe into bribery allegations

Greece’s investigation follows a similar probe launched in South Korea last February and corruption allegations leveled by a Turkish whistleblower in March. In August, South Korean prosecutors indicted a half-dozen Novartis executives for issuing improper rebates to local doctors.

Ver:

Korea: Los conflictos de NOVARTIS...

NOVARTIS: y ahora...en Turkia, y en China y en Corea del Sur...


Also last year, Novartis agreed to pay $25 million to settle an SEC investigation into bribery allegations in China. 
According to the SEC, Novartis offered Chinese doctors lavish entertainment—including a junket to Chicago and Niagara Falls—and other inducements to boost prescriptions of its drugs in the country.

Ver:

Tu quoque Novartis mi...!


Novartis is not the only multinational drugmaker paying fines to the U.S. for foreign corruption. AstraZeneca agreed last year to pay $5.5 million to settle the SEC’s allegations of bribery in China.

Ver:

CHINA Glaxo, La "banda" de l@s 4 ( 四人幫) bandas o...de los tres?


 And in a settlement that dwarfs all the others, Israel-based generics giant Teva agreed last month to hand over $520 million to wrap up a raft of bribery allegations in Russia, Ukraine and Mexico, the largest-ever FCPA settlement for a drugmaker.

Ver:

TEVA: Corrupción "en genérico"...

GSK y otr@s...(Pfizer, Roche, Novartis, Sandoz, Teva...) ahora "Corrupción a la Romania..."


Lo intentaste pero...
 

NOVARTIS: Joe perdió la confianza...y contrata un "Chief Ethics Officer"


(*)De poco te sirvió Joe Jimenez, según parece...

martes, 29 de marzo de 2016

Patient View 2015 Ranking (I) Corporate reputation


INDUSTRY-WIDE FINDINGS 

2015 was a watershed year for pharma’s investment in relationships with patient groups and patientcentric activities. 
Many of the major pharma companies announced new strategies to expand their patient centricity (some are outlined in this latest report). 
The step-up in interest among patient groups can be seen in the fact that ...

  •   The pharma industry's corporate reputation stands, in 2015, at its best ever since these PatientView surveys began in 2011. 44.7% of the 1,075 respondent patient groups stated that pharma had an “Excellent” or “Good” corporate reputation in 2015, compared with 34% in 2012 (when the industry’s corporate reputation reached its lowest ebb). 28% of 2015’s respondent patient groups believed the industry’s corporate reputation to have improved during the year.

  •    The main reason given by patient groups for the positive feedback in 2015 was pharma’s ability to produce highquality products of value to patients. As many as 72% of the 1,075 patient groups responding to the 2015 ‘Corporate Reputation of Pharma’ survey stated that the pharma industry as a whole was “Excellent” or “Good” during the year at producing high-quality products. This finding is the highest percentage that PatientView has ever recorded for this particular question throughout the five years in which the ‘Corporate Reputation’ survey has been conducted. 

Ver tambien:

ViiV y AbbVie reconocidos por PatientView como líderes.2015


However, patient groups retain reservations about pharma—in particular, about the industry's pricing practices ...

  • Only 15% of the patient groups responding to the 2015 survey stated that pharma was “Excellent” or “Good” at having fair pricing policies (and at not making excessive profits). As many as 45% of 2015’s respondent patient groups said that pharma was poor at this activity. 

  • The patient groups most aggrieved about pharma’s pricing are those specialising in hepatitis, HIV/AIDS, and rare diseases. In country terms, the most unhappy are patient groups in Australasia, France, Germany, the Netherlands, the UK, and the USA.

Ver