Conoce a David Brennan, CEO Astra

It’s hard to tell with Brennan, 56, who is a consummate salesman and charmer. Tall, urbane and spryly assertive, he has the clean-cut good looks of an American sports star, plus the droll sense of humour of an experienced raconteur.

All of that underscores a ferocious work ethic that has enabled him to jet back and forth to Washington while also heading a FTSE top 10 giant, worth £40 billion by market value here. And so far it looks as if American-born Brennan, the only top five pharma boss to come up through sales, has played a canny game on both continents.

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