miércoles, 6 de enero de 2016
Con Metformina vivir >100 años
Scientists think the best candidate for an anti-ageing drug is Metformin, the world’s most widely used diabetes drug which costs just 10p a day. Metformin increases the number of oxygen molecules released into a cell, which appears to boost robustness and longevity.
When Belgian researchers tested metformin on the tiny roundworm C.elegans the worms not only aged slower, but they also stayed healthier longer. They did not slow down or develop wrinkles. Mice treated with metformin increased their lifespan by nearly 40 per cent and their bones were also stronger. Last year Cardiff University found that when patients with diabetes were given the drug metformin they in fact lived longer than others without the condition, even though they should have died eight years earlier on average.
The new clinical trial called Targeting Aging with Metformin, or TAME, is scheduled to begin in the US next winter. Scientists from a range of institutions are currently raising funds and recruiting 3,000 70 to 80 year olds who have, or are risk of, cancer, heart disease and dementia. They are hoping to show that drug slows the ageing process and stops disease. (Más)